Products – Anmol Chemicals Private Limited
Sodium Salicylate USP
Abstract
Sodium salicylate is a sodium salt of salicylic acid. It can be prepared from sodium phenolate and carbon dioxideunder higher temperature and pressure. Historically, it has been synthesized from methyl salicylate (found in wintergreen plants or the bark of sweet birch tree) by reacting it with an excess of sodium hydroxide and heating it under reflux.
Use/Application
Sodium salicylate is used in medicine as an analgesic and antipyretic. Sodium salicylate also acts as non-steroidal anti-inflammatory drug (NSAID), and induces apoptosis in cancer cells and also necrosis. It is also a potential replacement for aspirin for people sensitive to it. It may also be used as a phosphor for the detection of vacuum ultraviolet radiation and electrons.
Identity
Chemical Name: Sodium Salicylate
Synonyms: Salsonin, Monosodium salicylate
Mol. Formula: C7H5NaO3
Mol. Wt.: 160.10 g/mol
CAS No.: 54-21-7
General Specifications
| Test | Specification…USP |
| Characters | It occurs as amorphous or microcrystalline powder or scales. Is colorless, or has not more than a faint, pink tinge. |
| Identification
Test (A) Test (B) Test (C) |
(a)Infrared Absorption (b) It gives reaction of Sodium (c) Specified test |
| Solubility | Very soluble in boiling water and in boiling alcohol; freely (and slowly) soluble in water and in glyclubrierin; slowly soluble in alcohol. |
| Sulfite or thiosulfate | Not more than 0.15 mL of 0.10 N iodine is required to produce a yellow color in the filtrate. |
| Organic impurities(total) | Not more than 0.2% |
| Water determination | Not more than 0.5% |
| Heavy metals | Not more than 20 ppm |
| Residual solvents | Meets the requirements |
| Assay | Not less than 98.0% and not more than 102.0%calculated on the anhydrous basis. |
Shelf life, Storage and Packing
It should be stored in a segregated area in a cool and ventilated place away from combustible materials. Keep in a tightly closed container, sealed until ready for use. It is packed in 25kg or 50kg HDPE bags or drums as required.
Other
We Manufacture Bulk Dugs/API, Excipients, pharmaceuticals (IP/BP/USP/NF/PH. EUR./JP), Speciality Chemicals (Pure/AR/ACS), mineral fortifiers (FCC). our manufacturing facility is GLP, GMP (FDA) approved, ISO 9001, ISO 14001, ISO 22000, FSSC 22000, FSSAI, kosher, halal, COPP and WHO-GMP certified.
Good Manufacturing Practice Certified by World Health Organization (WHO-GMP)
Written Confirmation Certification (WC)
Good Manufacturing Practice (EXCiPACT cGMP)
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